Metabolic Syndrome (METS) is a global health issue, associated with cardiovascular disease, common cancer, mortality, and huge social economic burden, especially in the elderly population. In recent decades, METS's prevalence has increased, and it has reached an amazing speed in the world. In 2016, the World Health Organization estimates that one-in-one adult population in the world will suffer from METS in his life, and the impact of its well-being and health systems is huge. Therefore, it is important to understand the risk factors that can be changed.
China is the country in the world, may endorse METS's maximum burden. It is estimated that one-third of Chinese adults are troubled by METS. At the same time, tea, especially green tea, very popular among middle-aged and elderly people in China. Suzhou is one of the most important green tea production districts in China. Drinking tea is a common living habit of a general population. Recent evidence shows that tea consumption is related to METS, but this effect seems to have controversy. Tea and METS existing mutual contradictions may be due to lack of longitudinal research design. The purpose of this study was to explore the forward-looking association between tea consumption and METS 5 years.
This study eventually covered 3005 participants. The average age of follow-up is 70.7 ± 5.7 years (range: 65.0 ~ 76.4). In the remaining 3005 baseline investigations, there were 1077 habital drinking tea and 1928 non-habital drinking tea. Table 1 The baseline characteristics of habitual drinking tea and non-disabled drinking tea are compared. In general, habitual drinking tea is more likely to be male (P <0.001), current smokers (P <0.001), drinkers (P <0.001), and have been well-educated (P <0.001), they also tend to With the spouse (P <0.001), the income is higher (P <0.001), and there are more physical activities (P <0.001).
Among the 3005 subjects without METS, 406 participants (accumulated incidence: 13.5%) were suffocated in five years of follow-up examination. We have found that the increase in the frequency of drinking tea is related to the decrease in the shrinkage period and the reduction in HDL-C levels (all trend P <0.001). Other ingredients such as BMI, diastolic BPS, blood FPG and Tg are not significantly correlated.
The results of sensitivity analysis are shown in Figure 1. We choose age, gender, initial BMI, education level, monthly income and marital status as a mixed factor to be controlled. Further studies the potential association between the tea and METs, as shown in Table 2. After adjusting the statistical characteristics of baseline population (such as initial BMI, education level, monthly income and marital status (model 2)), habitual drinking tea is suffering from non-customary drinking tea during 5 years The risk of METS increased by 31% (OR = 1.31, 95% CI: 1.1 -1.71; P = 0.04). However, no significant correlation was observed in men (OR = 1.38, 95% CI: 0.98-1.95; P = 0.06) or female (OR = 1.17, 95% CI: 0.76-1.79; P = 0.48) did not observe significant associations. Accordingly, compared with non-habitual drinking tea, a 5-year cumulative incidence of more than 5 times a week (OR = 1.38, 95% CI: 1.05-1.82; P = 0.02). This relationship is still present in men (OR = 1.43, 95% CI: 1.00-2.01; p = 0.05), but it is not significant in women (OR = 1.28, 95% CI: 0.79- 2.08; P = 0.32). At all research participants (OR = 1.27, 95% CI: 0.97-1.67; P = 0.09), male (OR = 1.26, 95% CI: 0.91-1.76; P = 0.17) and women (OR = 1.22, 95%) Ci: 0.75-1.99; P = 0.42) The correlation between the incidence of green tea intake and metabolic syndrome is not significant. Drinking tea 16-30 years compared to those who are not used to drinking tea, the participants in 16-30 are easier to suffer from METS (OR = 1.53, 95% CI: 1.02-2.28; P = 0.04). The results were statistically significant in men (OR = 1.39, 95% CI: 0.85-2.28; P = 0.19) or women (OR = 1.79, 95% CI: 0.87-3.71; P = 0.11) were statistically significant.
Figure 2 shows the potential association between the intake of the tea and the potential association between the METS single ingredient. There is no significant relationship between tea consumption and high blood pressure, high BMI, diabetes or low HDL-C levels during baseline. In model 1 (OR = 1.34, 95% CI: 1.03-1.73; P = 0.03) and model 2 (OR = 1.32, 95% CI: 1.02-1.72; p = 0.04), drink tea and high Tg And after the gender layers, men still have significant associations (OR = 1.47, 95% CI: 1.03-2.10; p = 0.03). Considering that the frequency of male drinking tea is much higher than women, we have a gender layered analysis, as shown in Figure 1. Sex may be the possible influencing factors associated between habitual drinking tea and METS single components. We found that the low HDL-C levels of men were related to drinking tea (OR = 2.03, 95% CI: 1.11-3.69; P = 0.02). However, for women, drinking tea is positively correlated with high BMI and blood pressure. In addition, in the model 2, female drinking tea is associated with diabetes (OR = 2.02, 95% CI: 1.07-3.83; P = 0.03). No interaction between the drinking tea and other variables was observed.
In general, 406 participants (accumulated incidence: 13.5%) have appeared in five years of follow-up test in 3005 baselines without METS. The regression analysis found that more than 5 years of the 5-year incidence of more than 5 times a week (OR = 1.38, 95% CI: 1.05-1.82; p = 0.02). This relationship still exists in men (OR = 1.43, 95% CI: 1.00-2.01; P = 0.05). In the five main components of METS, men are manifestative as low HDL-C levels, while women are manifested as high-strength indexes, high blood pressure and diabetes.
This 5-year priority study for Chinese elderly is found that drinking tea than 5 times a week, more than 5 people, more than 5 times, is higher than those who don't get used to drink tea. The dose-reaction relationship is also observed that the increase in green tea drinking frequency is related to the high risk of METS. In addition, the link between tea and METS single ingredients is different between men and women. These findings have added new knowledge for the current literature on tea to have controversial affected by cardiovascular and metabolic health of the elderly.
DONG et al. Habitual TEA Consumption and 5-year Incident Metabolic SYNDROME AMONG OLDER ADULTS: A Community-Based Cohort Study.BMC Geriatrics (2021) 21: 728
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